HPLC Column, RP C4 Butyl, 5um, 4.6mm ID x 50mm Length, 100A. Cogent Brand. 1 EA.
Additional Information:
Cogent RP C4™ is a reversed-phase HPLC stationary phase designed for the separation of hydrophobic and neutral compounds where less retention is desired than with traditional C8 or C18 phases. Manufactured using a four-carbon butyl ligand bonded to ultra-high purity silica and fully double end capped, this stationary phase provides reproducible chromatographic performance and is widely used as an alternative in USP methods requiring L26 chemistry. Its reduced hydrophobicity compared to longer-chain bonded phases makes it particularly useful for rapid analyses and method development studies.
68504-05P is an HPLC column packed with 5 µm RP C4™ particles featuring a 100 Å pore size in a 4.6 mm ID x 50 mm format. The short 50 mm length is optimized for fast analyses and high-throughput workflows, while the 5 µm particle size allows operation at higher flow rates with lower backpressure than smaller particle columns. Typical operating flow rates are approximately 1.0–2.0 mL/min depending on mobile phase composition, temperature, and system configuration.
This column is commonly used for hydrophobic and neutral compounds in reversed-phase HPLC when reduced retention is desirable. The C4 bonded phase is often selected for scouting studies, method development, and rapid screening applications where shorter run times and faster equilibration are beneficial.
Key Benefits
RP C4™ stationary phase
USP L26 equivalent chemistry
Butyl bonded phase
Fully double end capped
Ultra-high purity silica support
Less retention than C8 phases
Suitable for rapid analyses
Lower backpressure than smaller particle columns
5 µm particle size
Excellent for method scouting
Typical Applications
USP L26 methods
Method development
Method scouting
Hydrophobic compound analysis
Neutral compound analysis
Reversed-phase HPLC
Pharmaceutical analysis
Quality control testing
High-throughput analysis
Research and development
Specifications
Product Type: HPLC Column
Stationary Phase: RP C4™
USP Classification: L26
Chromatography Mode: Reversed Phase
Bonded Phase: Butyl (C4)
Endcapping: Fully Double End Capped
Particle Size: 5 µm
Pore Size: 100 Å
Column Dimensions: 4.6 mm ID x 50 mm
Length: 50 mm
Typical Flow Rate: 1.0–2.0 mL/min
Brand: Cogent
Important Notes
Designed for hydrophobic and neutral compounds
Provides less retention than C8 stationary phases
Suitable for rapid reversed-phase separations
The 50 mm length is ideal for short run times and high sample throughput
5 µm particles allow higher flow rates with lower backpressure
Fully double end capped to minimize secondary interactions
Frequently used for method development and scouting studies
Excellent alternative for USP L26 methods